Which of the following diseases must all clinical dental personnel be vaccinated against before working at the chairside?

All clinical dental personnel must be vaccinated against Hepatitis B before working at the chairside due to the significant risk of exposure to blood and other potentially infectious materials inherent in dental practice. Hepatitis B is a highly contagious virus that can lead to serious liver disease and even death. Vaccination provides a critical layer of protection for dental staff, patients, and the broader community.

The Hepatitis B vaccine is part of standard health protocols in dental settings, and it is recommended by health authorities such as the Centers for Disease Control and Prevention (CDC). Receiving the vaccine not only protects clinical staff from infection but also helps maintain a safer environment for patients, as healthcare workers might inadvertently transmit infections if they are not immunized.

Other diseases in the options, such as AIDS and Creutzfeldt-Jakob disease, either do not have a vaccine or do not pose the same degree of risk in a dental setting. Similarly, while there is a concern surrounding Hepatitis C, as there is no vaccine available for it, the highest priority for vaccination to prevent transmission in clinical dental practice remains Hepatitis B.